Chemical Mutagens: Principles and Methods for Their by Ilse-Dore Adler, J. Grant Brewen (auth.), Frederick J. de

By Ilse-Dore Adler, J. Grant Brewen (auth.), Frederick J. de Serres, Alexander Hollaender (eds.)

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1-4 days First Mouse Pos. p. p. p. p. 25 i. p. 1-23 days 9, 15,21 days 1-3 weeks 1-3 weeks 3-23 days First First First 4-8 cells 4-8 cells Mouse Mouse Mouse Mouse Chinese hamster Pos. Pos. Pos. Pos. Pos. -D. Adler and K. Fagan (unpublished). mass will be formed by only one cell, and the offspring will be of homogeneous genotype. (52) Thus, unlike in Drosophila, where a mosaic at the 2-cell stage may lead to a mosaic adult,(1l6) this is not the case in mice and probably not in mammals in general.

P. p. p. p. p. p. Styrene oxide TEM Tris (l-aziridinyl) phosphine oxide (TEPA) • (RT) Reciprocal translocations. p. p. p. p. p. p. p. p. 5 months 8-10 weeks 8 weeks 50-60 days 40 Days 3 months 3 months 3 months 30 days 8 weeks 12 weeks 8 weeks Intervals (DBAl2J) (ICR) (BALBIc) (BALB/c) (CD1) Guinea pig Golden hamster Mouse Mouse Mouse Mouse Mouse Mouse (BALB/c) Mouse [(101 x C3H) Fd Mouse (CD1) Mouse (101 x C3H) Rat (Wistar) Mouse (albino) Mouse (BALB/c) Mouse Mouse [(101 x C3H) Fd Mouse (CBA) Mouse (Swiss) Mouse (CBA) Species Neg.

M. Degraeve, J. Moutschen, M. Moutschen-Dahmen, J. Gilot-Delhalle, N. Houbrechts, and A. Colizzi, Cytogenetic and genetic effects of Phosan-plus, Mutat. Res. 46,204 (1977). 33. R. P. Donahue, Maturation of the mouse oocyte in vitro. II. Anomalies of the first polar body formation, Cytogenetics 9, 106-115 (1970). 34. R. P. Donahue, Cytogenetic analysis of first deavage division in mouse embryos, Proc. Natl. Acad. Sci. A. 69, 74-77 (1972). 35. R. G. Edwards and A. H. Gates, Timing of the stages of the maturation divisions, ovulation, fertilization and first cleavage of eggs of adult mice treated with gonadotropins,].

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